検索結果

Search Results for " Lipoic acid "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T17316	α-Lipoic acid-NHS	DL-α-Lipoic acid-NHS	Others
	α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs [1].		Others
T21233	Dihydrolipoic acid	Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid	Antioxidant
	Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydr...		Antioxidant
T26599	Alpha-Lipoic Acid Choline Ester	EV-06,EV 06,alphaLACE,alpha-LACE,EV06,alpha LACE
	Alpha-Lipoic Acid Choline Ester is used potentially to treat presbyopia.
T6157	Devimistat	CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid	Apoptosis , Dehydrogenase , Mitochondrial Metabolism
	Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potent...		Apoptosis , Dehydrogenase , Mitochondrial Metabolism
T35628	AN-7
	α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant. AN-7...
T37827	CAY10506	CAY10506
	Anti-diabetic drugs of the thiazolidinedione (TZD) structural class as well as α-lipoic acid activate peroxisome proliferator-activated receptor γ (PPARγ), a nuclear transcription factor that controls glucose metabolism ...
T21234	(R)-Dihydrolipoic acid
	(R)-Dihydrolipoic acid is a R-isomer of Dihydrolipoic acid. It is optically active, but only the R-enantiomer is biochemically significant. The lipoic acid/dihydrolipoic acid pair participate in a variety of biochemical ...
T73547	CPUL1
	CPUL1, a TrxR inhibitor, exhibits proliferation-inhibitory and anti-metastatic effects on A549 cells by modulating epithelial-mesenchymal transition (EMT) through the induction of ROS-mediated ERK/JNK signaling, achieved...
T74496	LA-Bac8c
	LA-Bac8c, a lipoic acid-modified antimicrobial peptide, exhibits improved antimicrobial efficacy. It effectively inhibits S. aureus, MRSA, S. epidermidis, E. coli, and P. aeruginosa, demonstrating minimum inhibitory conc...

Compounds

α-Lipoic acid-NHS

T17316

Synonym: DL-α-Lipoic acid-NHS

Target: Others

Dihydrolipoic acid

T21233

Synonym: Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid

Target: Antioxidant

Alpha-Lipoic Acid Choline Ester

T26599

Synonym: EV-06,EV 06,alphaLACE,alpha-LACE,EV06,alpha LACE

Target:

Devimistat

T6157

Synonym: CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid

Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism

(R)-Dihydrolipoic acid

カタログ番号	製品名	別名	ターゲット
T22235	Lipoic acid	R-(+)-Thioctic acid,(R)-(+)-1,2-Dithiolane-3-pentanoic acid,(R)-(+)-α-Lipoic acid	Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite
	Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.
T2930	α-Lipoic Acid	Lipoic acid,Alphalipoic acid	NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite
	α-Lipoic Acid (Alphalipoic acid) inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.α-Lipoic Acid is an antioxidant, which is an es...
T0200	α-Lipoic Acid	Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid	Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite
	α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ...
T72429	α-Lipoic Acid sodium	Thioctic acid sodium,DL-α-Lipoic acid sodium,Thioctic acid sodium ; (±)-α-Lipoic acid sodium ; DL-α-Lipoic acid sodium,(±)-α-Lipoic acid sodium
	α-Lipoic Acid (Thioctic acid) sodium, an essential cofactor for mitochondrial enzyme complexes, serves as an antioxidant. It suppresses NF-κB-dependent activation of HIV-1 LTR [1] [2] [3] and triggers ER (endoplasmic ret...

天然物製品

Lipoic acid

T22235

Synonym: R-(+)-Thioctic acid,(R)-(+)-1,2-Dithiolane-3-pentanoic acid,(R)-(+)-α-Lipoic acid

Target: Reactive Oxygen Species, Mitochondrial Metabolism, Endogenous Metabolite

α-Lipoic Acid

T2930

Synonym: Lipoic acid,Alphalipoic acid

Target: NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

α-Lipoic Acid

T0200

Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid

Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

α-Lipoic Acid sodium

T72429

Synonym: Thioctic acid sodium,DL-α-Lipoic acid sodium,Thioctic acid sodium ; (±)-α-Lipoic acid sodium ; DL-α-Lipoic acid sodium,(±)-α-Lipoic acid sodium

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00692	MTA/SAH nucleosidase Protein, E. coli O9:H4, Recombinant (His & Myc)	E. coli	E. coli
	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocy...
TMPY-03503	GCSH Protein, Human, Recombinant (His)	Human	E. coli
	Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoi...
TMPY-04568	PDK1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Pyruvate dehydrogenase kinase, isozyme 1, also known as [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial and PDK1, is a member of the PDK / BCKDK protein kinase family. PDK-1 is expressed predominantl...

MTA/SAH nucleosidase Protein, E. coli O9:H4, Recombinant (His & Myc)

TMPH-00692

Species: E. coli

Expression System: E. coli

GCSH Protein, Human, Recombinant (His)

TMPY-03503

Species: Human

Expression System: E. coli

PDK1 Protein, Human, Recombinant (His)

TMPY-04568

Species: Human

Expression System: Baculovirus Insect Cells